Table 1 Datasets used in this study
From: Integrative epigenetics and transcriptomics identify aging genes in human blood
Dataset Name | Data type | Data Source | Assay Type | Cell Type | #Samples | after filter | Accession ID |
|---|---|---|---|---|---|---|---|
MGB500 | DNAm | Mass General Biobank | Infinium MethylationEPIC v2 | PBMC | 500 | 461 | This study |
MGB4K | DNAm | Mass General Biobank | Infinium MethylationEPIC v1 | PBMC | 4243 | 4243 | Not public |
GS | DNAm | Generation Scotland | Infinium MethylationEPIC v1 | WB | 20,232 | 18,859 | |
MESA1 (DNAm) | DNAm | NHLBI TOPMed MESA, year 2000 | Infinium MethylationEPIC v1 | PBMC | 886 | 886 | phs001416.v3.p1 |
MESA2 (DNAm) | DNAm | NHLBI TOPMed MESA, year 2010 | Infinium MethylationEPIC v1 | PBMC | 888 | 888 | phs001416.v3.p1 |
PPMI (DNAm) | DNAm | Parkinson’s Progression Markers Initiative | Infinium MethylationEPIC v1 | WB | 1638 | 510 | via LONI IDA |
RA | DNAm | Epidemiological Investigation of Rheumatoid Arthritis | Infinium Methylation450K | PBL | 689 | 689 | GSE42861 |
Grady | DNAm | Grady Trauma Project | Infinium MethylationEPIC v1 | WB | 795 | 795 | GSE132203 |
GENOA | DNAm | Genetic epidemiology network of Arteriopathy | Infinium MethylationEPIC v1 | PBL | 1218 | 946 | GSE157131 |
MESA1 (RNA) | RNA-Seq | NHLBI TOPMed MESA, year 2000 | Illumina Sequencing | PBMC | 1016 | 1016 | phs001416.v3.p1 |
MESA2 (RNA) | RNA-Seq | NHLBI TOPMed MESA, year 2000 | Illumina Sequencing | PBMC | 845 | 845 | phs001416.v3.p1 |
PPMI (RNA) | RNA-Seq | Parkinson’s Progression Markers Initiative | Illumina Sequencing, 2 × 125 bp PE | WB | 1600 | 1111 | via LONI IDA |
JenAge | RNA-Seq | Jena Center for Systems Biology of Ageing | Illumina TruSeq 2.0 | WB | 62 | 62 | GSE103232 & GSE75337 |
GC6 | RNA-Seq | Gates Foundation Grand Challenges 6–74 program (Healthy Controls) | Illumina TruSeq stranded mRNA, 2 × 50bp PE | WB | 327 | 327 | GSE94438 |
500FG | RNA-Seq | 500 Functional Genomes Project | Illumina TruSeq 2.0, 2 × 50bp PE | WB | 100 | 100 | GSE134080 |
