Fig. 2: Substrate scope for the synthesis of C─N axially chiral carbazolyl indoles 2. | Nature Communications

Fig. 2: Substrate scope for the synthesis of C─N axially chiral carbazolyl indoles 2.

From: Copper-catalyzed atroposelective hydroarylation of 1-alkynylindoles

Fig. 2: Substrate scope for the synthesis of C─N axially chiral carbazolyl indoles 2.The alternative text for this image may have been generated using AI.

Reaction conditions: 1 (0.1 mmol), Cu(CH3CN)4PF6 (0.01 mmol), L14 (0.012 mmol), DCE (4 mL), −10 °C, in vials; yields are those for the isolated products; ee values are determined by HPLC analysis. aL10 (0.012 mmol). bL8 (0.012 mmol), 15 °C. cent-L14 (0.012 mmol).

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