Fig. 4: Network-level organization and cross-condition consistency of cortical gradients.
From: Methylphenidate reorganizes cortical hierarchy through dopaminergic modulation
a The 12 cortical network partitions of the iCSC-438 atlas overlaid on lateral and medial surface views of the left and right hemispheres. Scatter plots showing the strong linear association between principal (a) or secondary (b) gradient strengths in the placebo (PL) and methylphenidate (MP) conditions across 438 brain regions. In (b, c), data points are color-coded by network assignment29: Visual (VIS1, VIS2), Somatomotor (SMM), Cingulo-Opercular (CON), Dorsal Attention (DAN), Language (LAN), Frontoparietal (FPN), Auditory (AUD), Default-Mode (DMN), Posterior Multimodal (PMM), Ventral Multimodal (VMM), and Orbito-Affective (ORA). Diagonal lines indicate absence of MP-effects. Pearson correlations were tested using two-sided p-values. Source data are provided as a Source Data file.
