Fig. 5: White matter tractography and functional connectivity show connections from thalamus and primary auditory cortex to frontal lobe areas.
From: Parallel encoding of speech in human frontal and temporal lobes
A White matter tractography between the medial geniculate body (MGB), Heschl’s gyrus (HG), and suprasylvian cortex (IFG, middle precentral gyrus (mPreCG), and ventral sensorimotor cortex (vSMC)). White matter tracts are color-coded by the suprasylvian site of termination. This analysis demonstrates tractography data consistent with direct MGB-to-frontal cortex and HG-to-frontal cortex white matter tracts. B Resting-state functional connectivity of the medial geniculate body and C Heschl’s gyrus showing functional connectivity to frontal lobe areas, middle precentral gyrus, ventral sensorimotor cortex, and inferior frontal gyrus (connectivity maps derived by performing one-sample t-tests, one-sided, with a statistical threshold of p < 5 × 10−5 after peak-level family wise error (FWE) correction for multiple comparisons). Colorbar represents T-score. Overall, these data provide additional structural and functional evidence for parallel pathways to frontal lobe areas from low-level areas, such as Heschl’s gyrus and the medial geniculate body. CS central sulcus; FC functional connectivity; HG Heschl’s gyrus; IFG inferior frontal gyrus; IC inferior colliculus; MGB medial geniculate body; mPreCG middle precentral gyrus; vSMC ventral sensorimotor cortex.
