Fig. 3: Interactions between the IL-17RA SEFIR domain and ACT1.
From: Structural basis for ACT1 oligomerization induced by IL-17 receptor hetero-tetramer
a Overall structure of the IL-17RA/RB/ACT1 complex in cartoon and schematic representations. For simplicity, only two ACT1 protomers are shown to illustrate their interactions with IL-17RA. b Detailed view of the intra-strand interaction between the SEFIR domains of IL-17RA and ACT1. c Detailed view of the inter-strand interaction between the SEFIR domains of IL-17RA and ACT1. d Detailed view of the interaction between the β-hairpin of IL-17RA and the C-terminal extension of ACT1.
