Fig. 2: Macromolecular densities within cellular compartments are tightly regulated.
From: Maintenance of cytoplasmic and membrane densities shapes cellular geometry in Escherichia coli
The major macromolecular densities as a function of the growth rate in (a) the cytoplasm, b the membranes, and c the periplasmic space. d The ratio of the cytoplasmic and membrane densities as a function of the growth rate. Points calculated from mass spectrometry data as described in boxes. Total protein mass \({M}_{prot}^{(tot)}\) and total RNA mass \({M}_{RNA}^{(tot)}\) per cell for each sample was empirically determined from independent quantification as described in the Supplementary Note 3. Points represent the mean value of the posterior probability distribution for each quantity. Extent of the thin and thick error bars correspond to the 95% (approximately 2σ) and 68% (approximately 1σ) credible regions of the posterior distribution, respectively. Dashed lines represent fits to the mean values. See also Supplementary Fig. 4 for a comparative analysis of densities using different data compiled from the literature.
