Fig. 4: Comparison of the cryo-EM structures of cardiac IGLV1-44 fibril and renal IGLV1-44 fibril.
From: Cryo-EM structure of renal AL amyloid fibrils from a patient with λ1 light chain amyloidosis
a Cryo-EM structure of the cardiac IGLV1-44 fibril. The fibril is shown in pale yellow. A magnified view of the boxed region highlights key residues in a schematic representation, with residue numbers labeled. b Cryo-EM structure of the renal IGLV1-44 fibril. The fibril is shown in light pink. A magnified view of the boxed region highlights key residues in a schematic representation, with residue numbers labeled. c A structural alignment of the renal (colored in light pink) and heart (colored in pale yellow) IGLV1-44 fibrils.
