Fig. 1: CovidCatCentral Cohort history.

A Number of individuals in each of the CovidCatCentral cohort timepoints for the first-vaccinated and first-infected groups before study inclusion selection. The blue numbers represent the first-vaccinated, red numbers represent the first-infected, and the orange numbers show the total number of individuals at each time point. Magenta numbers indicate new individuals entering the study, darkgold numbers indicate individuals from any previous timepoints but not consecutive, and black numbers indicate individuals who followed up from one consecutive timepoint to the next. B Prevalence of the different COVID-19 variants circulating in Spain from 2020 to 2023 and related to the timepoints. C Temporal distribution of infections and vaccinations stratified by first exposure type among the analyzed population. Omicron infections started between T8 and T9. T: timepoint. Source data are provided in the source data.