Fig. 5: Transition states states (\(\phi \approx 0.5\)) of lipid flip-flop in plasma membrane mimetic at atomistic resolution.
From: AI-guided transition path sampling of lipid flip-flop and membrane nanoporation
a Halfway across the membrane, cholesterol tends to lie flat at the membrane center. b The polar head of PLPC lipid tends to retain a small hydration shell. Lipids and water are shown as sticks, phosphorus and cholesterol oxygen as spheres.
