Table 1 Demographic summary of participants in the study

From: Distinct diet-microbiome associations in autism spectrum disorder

 

CCDI (Tertile 1)

CCDI (Tertile 2)

CCDI (Tertile 3)

p-value

 

N = 273

N = 273

N = 272

 

Age

8.00 (7.00, 10.00)

8.00 (7.00, 10.00)

9.00 (7.00, 10.00)

0.130

Male

213 (78%)

191 (70%)

191 (70%)

0.056

ASD diagnosis

183 (67%)

152 (56%)

127 (47%)

<0.001

BMI

16.1 (14.7, 18.6)

16.0 (14.5, 18.6)

16.2 (15.1, 18.4)

0.700

Family medical history

38 (13.9%)

39 (14.3%)

35 (12.8%)

0.475

Comorbidity

88 (32%)

95 (35%)

76 (28%)

0.200

Medication use

51 (19%)

54 (20%)

45 (16%)

<0.001

GI symptoms

56 (21%)

29 (11%)

26 (9.5%)

<0.001

Bristol stool chart

 

<0.001

 Type 1, 2

65 (24.0%)

44 (15.8%)

39 (14.3%)

 

 Type 3, 4

147 (54%)

166 (61%)

177 (65%)

 

 Type 5, 6, 7

26 (9.6%)

22 (8.1%)

23 (8.5%)

 

Autistic symptoms

    

 SEQ-hyper

2.00 (1.64, 2.43)

1.86 (1.50, 2.29)

1.71 (1.50, 2.07)

<0.001

 SEQ-hypo

1.50 (1.17, 2.00)

1.50 (1.17, 2.00)

1.33 (1.17, 1.83)

0.048

 SRS-RRB

56 (48, 66)

54 (46, 66)

50 (45, 62)

0.002

 SRS-SCI

63 (55, 73)

61 (54, 71)

59 (52, 66)

<0.001

Eating behaviors (CEBQ)

    

 DD

2.67 (2.00, 3.33)

2.67 (2.00, 3.33)

2.33 (2.00, 3.00)

0.025

 EF

3.00 (2.50, 3.75)

3.25 (2.75, 3.75)

3.50 (2.75, 4.00)

<0.001

 EOE

1.75 (1.25, 2.25)

1.75 (1.25, 2.25)

1.75 (1.25, 2.00)

0.600

 EUE

2.75 (2.25, 3.25)

2.75 (2.25, 3.25)

2.50 (2.00, 3.25)

0.600

 FF

1.50 (1.17, 1.83)

1.33 (1.00, 1.67)

1.17 (1.00, 1.50)

<0.001

 FR

2.40 (2.00, 2.80)

2.40 (2.00, 2.80)

2.20 (2.00, 2.80)

0.200

 SE

2.25 (1.50, 2.75)

2.00 (1.63, 2.75)

2.00 (1.50, 2.75)

0.990

 SR

2.00 (1.80, 2.60)

2.00 (1.60, 2.40)

2.00 (1.60, 2.40)

0.044

  1. The study populations were categorized into tertiles of the Chinese Children Healthy Dietary Index (CCDI), indicating a less healthy dietary pattern with an average score of 63 (interquartile range [IQR]: 57, 67), a moderate quality with an average score of 76 (IQR: 73, 80), and a healthier pattern with an average score of 91 (IQR: 86, 96). Group comparisons were performed using Kruskal-Wallis rank sum tests for continuous variables, and Pearson’s Chi-squared tests were used for categorical variables. All reported exact p-values are two-tailed testing. BMI body mass index, GI gastrointestinal, CEBQ the Children’s Eating Behavior Questionnaire, DD desire for drinks, EF enjoyment of food, EOE emotional overeating, EUE emotional undereating, FF food fussiness, FR food responsiveness, SE slowness in eating, SR satiety responsiveness.