Table 2 The topological features of the microbial connection network according to the exposure levels of food emulsifiers
From: Distinct diet-microbiome associations in autism spectrum disorder
Polysorbate 80 | non-ASD | ASD | ||||
|---|---|---|---|---|---|---|
Parameters | Low (n = 143) | Moderate (n = 115) | High (n = 98) | Low (n = 130) | Moderate (n = 157) | High (n = 175) |
Number of edges | 85bc | 111bc | 119c | 76b | 57b | 45a |
Number of positive edges | 76bc | 105bc | 113c | 68b | 49b | 38a |
Number of negative edges | 9c | 6a | 6a | 8c | 8c | 7b |
Number of vertices | 59b | 70c | 75c | 47a | 53a | 39a |
Average degree | 2.881ab | 3.171ab | 3.173b | 3.234b | 2.151ab | 2.307a |
Average path length | 3.658a | 3.679a | 5.794a | 4.303a | 2.425a | 2.507a |
Clustering coefficient | 0.426ab | 0.458ab | 0.428ab | 0.558b | 0.333a | 0.361a |
Centralization degree | 7.241a | 7.942a | 8.946a | 7.934a | 8a | 7.894a |
Modularity (> 0.4) | 0.626a | 0.614a | 0.584a | 0.45a | 0.736a | 0.626a |
Number of modules | 11ab | 13ab | 14ab | 10ab | 14b | 9a |
Carrageenan | non-ASD | ASD | ||||
Parameters | Low (n = 142) | Moderate (n = 132) | High (n = 82) | Low (n = 131) | Moderate (n = 140) | High (n = 191) |
Number of edges | 67bc | 119bc | 79c | 69b | 70bc | 32a |
Number of positive edges | 64bc | 107bc | 74c | 64b | 64bc | 24a |
Number of negative edges | 3a | 12c | 5b | 5b | 6b | 8b |
Number of vertices | 51b | 73bd | 57c | 43b | 61b | 31a |
Average degree | 2.627bc | 3.26c | 2.772c | 3.209b | 2.295b | 2.064a |
Average path length | 4.965a | 5.212a | 2.193a | 2.173a | 2.761a | 2.799a |
Clustering coefficient | 0.574a | 0.47a | 0.672a | 0.594a | 0.275a | 0.328a |
Centralization degree | 6.441a | 9.875a | 7.357a | 9a | 5.8a | 5.1a |
Modularity (> 0.4) | 0.684a | 0.637a | 0.672b | 0.506a | 0.738ab | 0.658a |
Number of modules | 10ab | 13ab | 15c | 8b | 12a | 7a |