Table 2 Outcomes of ovarian stimulation and characteristics of embryo transfer
From: Zishen Yutai Pill increased live births in advanced maternal age women: a randomized clinical trial
Characteristics | ZYP group (n = 734) | Placebo group (n = 733) |
|---|---|---|
Protocol | ||
Long protocol | 518 (70.6) | 507 (69.2) |
Antagonist protocol | 193 (26.3) | 199 (27.1) |
Days of ovarian stimulation, days, median (IQR range) | 11 (9–13) | 11 (9–13) |
Gonadotropin dose, IU, median (IQR range) a | 1575.00 (656.25–2612.50) | 1500.00 (515.63–2475.00) |
Estradiol on hCG trigger day, pmol/L, median (IQR range) | 8826.35 (5794.93–13990.04) | 9446.58 (5449.95–14441.45) |
Progesterone on hCG trigger day, µg/L, median (IQR range) | 0.70 (0.48–1.05) | 0.70 (0.45–1.04) |
Luteinizing hormone on hCG trigger day, IU/L, median (IQR range) | 1.70 (1.05–2.64) | 1.55 (1.04–2.59) |
Endometrial thickness on hCG trigger day, mm, median (IQR range) | 11.00 (9.50–12.80) | 11.00 (9.25–12.80) |
Outcomes | ||
Number of oocytes retrieved, no., median (IQR range) | 9 (5, 13) | 9 (6, 13) |
Number of cleavage, no., median (IQR range) | 7 (4, 10) | 6 (4, 10) |
Number of 2PN fertilization, no., median (IQR range) | 6 (3, 9) | 6 (3, 9) |
Number of available embryos, no., median (IQR range) | 4 (2, 5) | 3 (2, 5) |
Number of high-quality embryos, no., median (IQR range) | 2 (0, 4) | 2 (0, 4) |
Method of fertilizationb | ||
IVF | 324 (76.8) | 318 (77.2) |
ICSI | 75 (17.8) | 63 (15.3) |
IVF + ICSI c | 23 (5.5) | 31 (7.5) |
Number of embryos transferred b | ||
1 | 148 (35.1) | 158 (38.3) |
2 | 270 (64.0) | 253 (61.4) |
3 | 4 (0.9) | 1 (0.2) |
The day of embryo-transfer b | ||
D2 | 5 (1.2) | 2 (0.5) |
D3 | 319 (75.6) | 320 (77.7) |
D4 | 2 (0.5) | 4 (1.0) |
D5 | 96 (22.7) | 86 (20.9) |
