Fig. 3: Reaction of benzofuran 1a with different N-propargyl ynamides 2.
From: Enantioselective dearomative single-atom skeletal editing of benzofurans
Reaction conditions: 1a (0.3 mmol), 2 (0.1 mmol), CuOAc (0.015 mmol), NaBArF4 (0.018 mmol), L10 (0.018 mmol), toluene (2 mL), 5 °C, 36–130 h, in vials; yields were those for the isolated products; ees were determined by HPLC analysis. aEnt-L10 was used instead of L10. b(S)-BINAP was used instead of L10, − 20 °C. PG = protecting group, Mbs = 4-methoxybenzenesulfonyl, Bs = 4-bromobenzenesulfonyl.
