Table 3 Further characteristics of breast cancer patients by antibiotic use after diagnosis in England and Wales
From: Antibiotic use and survival from breast cancer: A population-based cohort study in England and Wales
Characteristics | England | Wales | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
None | 1+ | 1–5 | 6–11 | 12+ | None | 1+ | 1–5 | 6–11 | 12+ | |
Deprivation | ||||||||||
1st fifth (deprived) | 1069 (13%) | 2802 (14%) | 1924 (13%) | 532 (14%) | 346 (15%) | 474 (14%) | 1798 (15%) | 996 (14%) | 397 (15%) | 405 (17%) |
2nd fifth | 1469 (18%) | 3549 (17%) | 2480 (17%) | 672 (17%) | 397 (17%) | 644 (19%) | 2257 (18%) | 1279 (18%) | 518 (19%) | 460 (20%) |
3rd fifth | 1664 (20%) | 4153 (20%) | 2901 (20%) | 790 (20%) | 462 (20%) | 653 (19%) | 2625 (21%) | 1524 (21%) | 576 (21%) | 525 (23%) |
4th fifth | 1925 (23%) | 4796 (23%) | 3347 (23%) | 908 (23%) | 541 (24%) | 714 (21%) | 2585 (21%) | 1599 (22%) | 567 (21%) | 419 (18%) |
5th fifth (affluent) | 2164 (26%) | 5159 (25%) | 3656 (26%) | 962 (25%) | 541 (24%) | 878-835 (26%) | 30625 (25%) | 1863-85 (26%) | 674-95 (25%) | 517-225 (22%) |
Myocardial infarction | 102 (1%) | 295 (1%) | 176 (1%) | 80 (2%) | 39 (2%) | 67 (2%) | 156 (1%) | 93 (1%) | 29 (1%) | 34 (1%) |
Heart failure | 88 (1%) | 236 (1%) | 159 (1%) | 53 (1%) | 24 (1%) | 96 (3%) | 206 (2%) | 117 (2%) | 49 (2%) | 40 (2%) |
PVDa | 58 (1%) | 176 (1%) | 104 (1%) | 45 (1%) | 27 (1%) | 58 (2%) | 176 (1%) | 97 (1%) | 37 (1%) | 42 (2%) |
Stroke | 221 (3%) | 634 (3%) | 404 (3%) | 130 (3%) | 100 (4%) | 139 (4%) | 420 (3%) | 240 (3%) | 95 (3%) | 85 (4%) |
COPDb | 75 (1%) | 345 (2%) | 188 (1%) | 76 (2%) | 81 (4%) | 127 (4%) | 543 (4%) | 275 (4%) | 122 (4%) | 146 (6%) |
Hemiplegia | 23 (0%) | 66 (0%) | 43 (0%) | 11 (0%) | 12 (1%) | 24 (1%) | 92 (1%) | 55 (1%) | 14 (1%) | 23 (1%) |
Dementia | 60 (1%) | 104 (1%) | 71 (0%) | 21 (1%) | 12 (1%) | 40 (1%) | 81 (1%) | 52 (1%) | 18 (1%) | 11 (0%) |
Liver diseases | 86 (1%) | 226 (1%) | 157 (1%) | 42 (1%) | 27 (1%) | 27 (1%) | 101 (1%) | 60 (1%) | 20 (1%) | 21 (1%) |
Peptic ulcer | 127 (2%) | 421 (2%) | 263 (2%) | 96 (2%) | 62 (3%) | 41 (1%) | 211 (2%) | 102 (1%) | 48 (2%) | 61 (3%) |
Diabetes | 529 (6%) | 1462 (7%) | 977 (7%) | 305 (8%) | 180 (8%) | 381 (11%) | 1405 (11%) | 828 (11%) | 315 (12%) | 262 (11%) |
Chronic kidney disease | 481 (6%) | 1234 (6%) | 838 (6%) | 274 (7%) | 122 (5%) | 229 (7%) | 669 (5%) | 402 (6%) | 155 (6%) | 112 (5%) |
Statin (after)3 | 1480 (18%) | 4038 (20%) | 2715 (19%) | 838 (22%) | 485 (21%) | 566 (17%) | 2431 (20%) | 1376 (19%) | 557 (20%) | 498 (21%) |
Aspirin (after)3 | 479 (6%) | 1788 (9%) | 1086 (8%) | 415 (11%) | 287 (13%) | 278 (8%) | 1319 (11%) | 687 (9%) | 312 (11%) | 320 (14%) |
Metformin (after)3 | 351 (4%) | 1004 (5%) | 658 (5%) | 215 (6%) | 131 (6%) | 137 (4%) | 504 (4%) | 285 (4%) | 111 (4%) | 108 (5%) |
HRT (before)4 | 1654 (20%) | 5217 (25%) | 3294 (23%) | 1102 (29%) | 821 (36%) | 631 (19%) | 3198 (26%) | 1697 (23%) | 757 (28%) | 744 (32%) |
Smoking: Current | 498 (6%) | 1375 (7%) | 910 (6%) | 295 (8%) | 170 (7%) | 413 (12%) | 1977 (16%) | 1108 (15%) | 438 (16%) | 431 (18%) |
Past | 1710 (21%) | 4819 (24%) | 3395 (24%) | 896 (23%) | 528 (23%) | 570 (17%) | 2470 (20%) | 1508 (21%) | 534 (20%) | 428 (18%) |
Never | 5073 (61%) | 11,717 (57%) | 8329 (58%) | 2159 (56%) | 1229 (54%) | 1863 (55%) | 6850 (56%) | 4086 (56%) | 1515 (55%) | 1249 (54%) |
Missing | 560 (7%) | 1164 (6%) | 744 (5%) | 234 (6%) | 186 (8%) | 522 (15%) | 1037 (8%) | 564 (8%) | 250 (9%) | 223 (10%) |
BMI: <18.5 | 137 (2%) | 219 (1%) | 163 (1%) | 36 (1%) | 20 (1%) | 38 (1%) | 121 (1%) | 78 (1%) | 24 (1%) | 19 (1%) |
18.5–24.9 | 2660 (32%) | 5949 (29%) | 4330 (30%) | 1076 (28%) | 543 (24%) | 917 (27%) | 3414 (28%) | 2120 (29%) | 732 (27%) | 562 (24%) |
25–29.9 | 2299 (28%) | 5855 (29%) | 4067 (28%) | 1138 (29%) | 650 (28%) | 822 (24%) | 3454 (28%) | 2022 (28%) | 769 (28%) | 663 (28%) |
≥30 | 1636 (20%) | 5014 (25%) | 3326 (23%) | 1016 (26%) | 672 (29%) | 669 (20%) | 3002 (24%) | 1655 (23%) | 695 (25%) | 652 (28%) |
Missing | 1559 (19%) | 3422 (17%) | 2422 (17%) | 598 (15%) | 402 (18%) | 922 (27%) | 2343 (19%) | 1391 (19%) | 517 (19%) | 435 (19%) |
Mean (s.d.) | 27.0 (6.0) | 27.7 (5.8) | 27.5 (5.7) | 28.0 (5.9) | 28.7 (6.2) | 27.2 (5.5) | 27.8 (5.8) | 27.5 (5.6) | 28.0 (5.7) | 28.6 (6.2) |
