Fig. 2: QTL mapping with CC strains identifies a 3.43 Mb locus on mouse chromosome 7 that associates with ILC2 prevalence after aeroallergen challenge. | Nature Communications

Fig. 2: QTL mapping with CC strains identifies a 3.43 Mb locus on mouse chromosome 7 that associates with ILC2 prevalence after aeroallergen challenge.

From: Genetic diversity of Collaborative Cross mice implicates FFAR3 as a target for ILC2 anti-inflammatory reprogramming

Fig. 2

A QTL map of ILC2 prevalence after Alt Ex challenge. LOD = Logarithm of Odds. Horizontal lines represent significance thresholds determined by permutation testing (80%, 90%, and 95% from bottom to top). No peaks other than our QTL of interest reached even the lowest significance threshold. B The haplotype effect of each founder in generating the significant QTL described in (A), termed Ch.7 ILC2 Locus. The bottom panel represents a zoomed-in view of the Ch.7 ILC2 Locus presented in (A) detailing chromosomal position.

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