Fig. 3: Exercise reshapes the immune cell proteome towards effector function and causes distinct alterations in protein abundance in response to HIIE and MICE.
From: Acute exercise rewires the proteomic landscape of human immune cells
A Gene Ontology (GO) over-representation analysis comparing significantly altered proteins in HIIE (n = 1377) and MICE (n = 64) with all proteins quantified in this study (n = 6039). B Overview of proteins altered by HIIE, MICE, or both exercise conditions. C Overview of proteins uniquely altered by HIIE. D Overview of proteins altered by both exercise conditions. The first two clusters identified by hierarchical clustering separate proteins displaying different kinetics in HIIE and MICE (1) from proteins displaying similar kinetics (2). E Overview of proteins uniquely altered by MICE. The first two clusters identified by hierarchical clustering separate proteins increasing in response to MICE (1) from proteins decreasing in response to MICE (2). See also Supplementary Data S5 and S6.
