Fig. 4: The effect of previous seasonal influenza vaccination on VSV-H5N1 cross-neutralizing antibody titres, H5- and group 1 HA stalk- reactive antibody titres.
From: Adjuvanted influenza vaccination increases pre-existing H5N1 cross-reactive antibodies
Log10 transformed antibody titres pre and post pH1N1/AS03 vaccination and fold changes grouped by whether participants have received a seasonal influenza vaccine only in 2008 (n = 7), 2009 (n = 13), in both years (2008 + 2009) (n = 50) or not (n = 56). A Neutralizing antibodies against VSV-H5N1 pseudoviruses. B IgG antibody binding titres to H5 HA from HPAIV H5N1 (A/Pelican/Bern/1/2022). C Antibody binding titres to group 1 HA stalk (cH6/1). All antibody titres have been log10 transformed. Mean and SD is shown. Kruskal-Wallis test (two-tailed) with Dunn’s test were performed to compare the mean rank of each column and to correct for multiple comparisons. Source data are provided as a Source Data file.
