Table 1 Patient demographics. Characteristics of JIA-uveitis and JIA patients included within the study
Characteristic | JIA-uveitis | % Missing data | JIA | % Missing data | P-value ( ≤ 0.05 values shown) |
|---|---|---|---|---|---|
Total samples (n) | 44 | – | 116 | – | < 0.0001 |
Total patients (n) | 43 | 115 | < 0.0001 | ||
Active uveitis n (%) | 29 (65) | N/A | N/A | ||
Recruitment years | 2010– 2019 | 1999–2019 | N/A | ||
Age at sample, years, median, (range) | 8.7 (1.7 – 16) | 0 | 9.1 (1.2 – 16.6) | 0 | – |
Age at disease onset, years, median (range) | 4.3 (0.4 – 11.9) | 0 | 5.6 (0.2 – 16) | 2 | – |
Sex n (%) | |||||
Female | 35 (79) | 0 | 74 (64) | 0 | – |
Male | 9 (21) | 0 | 42 (36) | 0 | – |
Ancestry n (%) | |||||
Non-Caucasian | 15 (35) | 0 | 25 (22) | 0 | – |
Caucasian | 29 (65) | 0 | 91 (78) | 0 | – |
JIA subtype n (%) | |||||
Oligoarticular – persistent | 15 (34) | 0 | 12 (10) | 0 | 0.0007 |
Oligoarticular – extended | 16 (36) | 0 | 26 (22) | 0 | – |
Polyarticular RF-ve | 11 (25) | 0 | 44 (38) | 0 | 0.0008 |
Polyarticular RF+ve | 2 (5) | 0 | 6 (5) | 0 | – |
Enthesitis-related | 0 (0) | 0 | 18 (16) | 0 | 0.0036 |
Psoriatic JIA | 0 (0) | 0 | 7 (6) | 0 | – |
Undifferentiated | 0 (0) | 0 | 1 (1) | 0 | Â |
‘Polygo’ | 42 (96) | 0 | 82 (70) |  | 0.0005 |
Active joint count, median, (range) | 4 (0-23) | 2 | 4 (0 – 34) | 0 | – |
ANA positive n (%) | 37 (84) | 0 | 61 (59) | 3 | 0.0074 |
RF positive n (%) | 4 (10) | 7 | 11 (10) | 9 | – |
HLA-B27 positive n (%) | 1 (8) | 70 | 16 (30) | 54 | Â |
Treatment at time of sample n (%) | |||||
MTX | 16 (36) | 0 | 18 (15) | 0 | 0.0084 |
Anti-TNF | 2 (5) | 0 | 0 (0) | 1 | – |
Anti-IL6 | 0 (0) | 0 | 0 (0) | 1 | – |
Topical eye steroids | 14 (32) | 0 | 0 (0) | 0 | N/A |
Systemic steroids | 8 (18) | 0 | 5 (4) | 1 | 0.0081 |
