Fig. 2: Substrate scope of alkyne. | Nature Communications

Fig. 2: Substrate scope of alkyne.

From: Atroposelective interrupted CuAAC reaction using cyclic diaryliodoniums

Fig. 2: Substrate scope of alkyne.The alternative text for this image may have been generated using AI.

Conditions: 1 (0.1 mmol), 2 (0.12 mmol), 3 (0.12 mmol), Cu(MeCN)4PF6 (0.010 mmol), L1 (0.02 mmol), 4 Å molecular sieves (80 mg), K2CO3 (3.0 equiv.) in CH2Cl2 (4 mL), and stirred at 25 °C for 36 h. Isolated yields are reported, and ee values were determined by chiral stationary HPLC.

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