Fig. 1: Development process of a unified prognostic staging system.
From: Biomarker-integrated prognostic stagings for Alzheimer’s Disease

a Overall scheme to develop a unified prognostic staging system. b Detailed process for feature selection and cutoff determination to identify prognostic risk subgroups in Phase 1. CU cognitively unimpaired, MCI mild cognitive impairment, Dem dementia, CDR-SB clinical dementia rating–sum of boxes.