Fig. 2: LNPDB includes diverse LNP data from 19,528 formulations across 42 studies. | Nature Communications

Fig. 2: LNPDB includes diverse LNP data from 19,528 formulations across 42 studies.

From: Lipid Nanoparticle Database towards structure-function modeling and data-driven design for nucleic acid delivery

Fig. 2: LNPDB includes diverse LNP data from 19,528 formulations across 42 studies.

a UMAP visualization of the high-dimensional embedding landscapes of LNP formulations (left) and unique ionizable lipids (right) compiled in LNPDB, colored according to originating study. b Summary statistics of ionizable lipids by molecular weight, number of nitrogens, and nitrogen substitution class. c Summary statistics of ionizable lipid (IL)-to-nucleic acid mass ratio, helper lipid type, and PEG lipid type. d Summary statistics of experimental properties by cargo, delivery target, and readout method. Additional summary statistics are shown in Supplementary Fig. 1. Source data are provided as a Source data file.

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