Fig. 4: Synthetic applications.

a Bromination of 3bb with Br2 in DCM. b NBS-mediated oxidative functionalization of 3bb in tBuOH/H2O followed by NaOH. c Hydrogenation of 4g over Pd/C under H2. d Reduction of 4g with BH3–THF.

a Bromination of 3bb with Br2 in DCM. b NBS-mediated oxidative functionalization of 3bb in tBuOH/H2O followed by NaOH. c Hydrogenation of 4g over Pd/C under H2. d Reduction of 4g with BH3–THF.