Fig. 3: Overlapping and differing affected areas in the brain across a first and second pregnancy.
From: The effects of a second pregnancy on women’s brain structure and function
Combining the cluster-corrected vertex-wise analyses of the multiparous (PRG2; n = 30) vs. control women (CTR; n = 40) and primiparous (PRG1; n = 40) vs. CTR resulted in three areas of interest: areas affected in both first and second pregnancies (Overlap; yellow), areas only affected in a first pregnancy (Only CTR-PRG1, magenta) and areas only affected in a second pregnancy (Only CTRL-PRG2; green) (a). We localized these areas according to the seven resting-state networks of Yeo27 (b). After calculating the expected overlap based on a random distribution across the gray matter in the brain, we calculated the observed/expected ratio for each area for each functional network (c). The horizontal line represents an observed/expected overlap of 1, meaning that the observed intersection of the area is similar as when there would be a random distribution across the brain. Spider plots representing the distribution across the seven Yeo networks for the three areas of interest (overlap: yellow; Only CTR-PRG1: magenta; Only CTR-PRG2: green) (d). Source data are provided as a Source Data file.
