Fig. 6: Study design.
From: The effects of a second pregnancy on women’s brain structure and function
We included second time mothers (multiparous; PRG2), first-time mothers (primiparous; PRG1) and control women (CTR) not getting pregnant in between the scans (CTR). We acquired structural T1-weighted, resting-state functional, diffusion-weighted MRI scans and a magnetic resonance spectroscopy (MRS) scan before pregnancy (Session 1: PRE), in the early postpartum period (Session 3; POST) and the late postpartum period (Session 4; POST1). The pregnancy session only included questionnaires, hormone sampling and cognitive testing, since MRI scanning was not allowed during pregnancy by the ethical committee. Icons in this figure were obtained from Font Awesome (https://fontawesome.com) and are used under the Creative Commons Attribution 4.0 International License (CC BY 4.0; https://creativecommons.org/licenses/by/4.0/). The icons were not adapted. Source data are provided as a Source Data file1. Hoekzema et al. (2022).
