Fig. 4: Modulation of dwell times by varying RNA and RNase H levels.

A–E Cumulative probability plots of dwell times under varying RNA concentrations (5, 10, 50,100 and 500 nM) with RNase H concentration held constant (80 nM). Blue: τO (time remains at unfold state); Red: τC (time remains at fold state). Each dataset was fitted using a double-exponential decay model. F Plot of τO and τC vs. RNA concentration (log scale). G–K Cumulative probability plots of dwell times under varying RNase H concentrations (11, 30, 55, 80 and 110 nM) with RNA concentration held constant (500 nM). Blue: τO; Red: τC. Each dataset was fitted using a double-exponential fit. L Plot of τO and τC vs. enzyme concentration. The τO and τC are expressed as mean +/− standard error based on 1000 bootstrap resamples. Source data are provided as a Source Data file.