Table 1 Baseline characteristics
Characteristics | Testosterone (N = 134) | Placebo (N = 154) |
|---|---|---|
Age (years) | 38.0 ± 3.5 | 38.1 ± 3.2 |
Age group, No. (%) | ||
<36 | 28 (20.9) | 25 (16.2) |
36 – 39 | 48 (35.8) | 70 (45.5) |
≥40 | 58 (43.3) | 59 (38.3) |
BMI (kg/m2) | 24.9 ± 4.6 | 24.2 ± 4.0 |
Current smoker, No. (%) | 21 (15.7) | 24 (15.6) |
Current alcohol use, No. (%) | 23 (17.2) | 32 (20.8) |
Median duration of infertility (IQR) (months) | 30 (18–48) | 24 (16–41) |
Cause of infertility, No. (%)a | ||
Andrological | 36 (26.9) | 39 (25.3) |
Endometriosis | 8 (6.0) | 13 (8.4) |
Ovulatory disorders | 24 (17.9) | 27 (17.5) |
Tubal factor | 9 (6.7) | 7 (4.5) |
Idiopathic | 21 (15.7) | 18 (11.7) |
Age-related | 28 (20.9) | 39 (25.3) |
Poor responder | 54 (40.3) | 60 (39.0) |
Other | 8 (6.0) | 25 (16.2) |
Number of previous IVF cycles, No. (%) | ||
0 | 20 (14.9) | 22 (14.3) |
1 | 42 (31.3) | 50 (32.5) |
2 | 27 (20.2) | 41 (26.6) |
≥3 | 45 (33.6) | 41 (26.6) |
Previous live birth, No. (%) | 25 (18.7) | 19 (12.3) |
Previous pregnancy loss, No. (%) | 40 (29.9) | 53 (34.4) |
Laboratory/imaging findings (screening visit) | ||
AFC (No.) | 4 (3–6) | 4 (3–6) |
AMH (ng/ml) | 0.45 (0.24–0.71) | 0.48 (0.21–0.85) |
FSH (IU/L) | 9.3 (6.6–14.2) | 9.9 (6.7–12.7) |
SHBG (nmol/L) | 71.8 (49.9–100.0) | 72.0 (49.9–95.0) |
T (nmol/L)b | 0.62 (0.36–0.90) | 0.77 (0.52–1.10) |
