Table 2 Clinical outcomes
Outcome | Testosterone (N = 134) | Placebo (N = 154) | Relative risk (95% CI) | P Value |
|---|---|---|---|---|
Primary outcome | ||||
Clinical pregnancy rate, No. (%) | 21 (15.7) | 23 (14.9) | 1.05 (0.61 to 1.81) | 0.86 |
IVF pregnancy | 20 (14.9) | 20 (13.0) | 1.15 (0.65 to 2.04) | 0.64 |
Spontaneous conception | 1 (0.7) | 3 (1.9) | 0.38 (0.04 to 3.64) | 0.63 |
Clinical pregnancy rate by age group, No. (%) | ||||
<36 | 5/28 (17.9) | 5/25 (20.0) | 0.89 (0.29 to 2.73) | 0.84 |
36-39 | 10/48 (20.8) | 14/70 (20.0) | 1.04 (0.51 to 2.15) | 0.91 |
≥40 | 6/52 (10.3) | 4/59 (6.8) | 1.53 (0.45 to 5.13) | 0.49 |
Secondary outcomes | ||||
Cycle cancellation, No. (%) | 31 (26.1) | 22 (16.7) | 1.56 (0.96 to 2.54) | 0.07 |
Reached embryo transfer, No. (%) | 67 (50.0) | 83 (53.2) | 0.94 (0.75 to 1.18) | 0.58 |
Biochemical pregnancy, No. (%) | 30 (22.4) | 31 (20.1) | 1.11 (0.71 to 1.74) | 0.64 |
Ongoing pregnancy rate, No. (%) | 15 (11.2) | 21 (13.6) | 0.82 (0.44 to 1.53) | 0.53 |
No. of fetal hearts detected, No./total (%) | ||||
1 | 17/21 (81.0) | 23/23 (100) | 0.81 (0.66 to 1.00) | 0.04 |
2 | 4/21 (19.0) | - | - | - |
Miscarriage, No./total (%) | 6/21 (28.6) | 3/23 (13.0) | 2.19 (0.63 to 7.67) | 0.27 |
Singleton | 5/17 (29.4) | 3/23 (13.0) | - | - |
Twin | 1/4 (25.0) | - | - | - |
Stillbirth, No./total (%) | 1/21 (4.8) | - | - | 0.48 |
Singleton | 1/21 (4.8) | - | - | - |
Twin | - | - | - | - |
Live birth, No. (%) | 14 (10.4) | 20 (13.0) | 0.80 (0.42 to 1.53) | 0.51 |
Singleton | 11 | 20 | - | - |
Twin | 3 | - | - | - |
