Fig. 4: Increased IL1R2 mainly expresses on CD11b⁺ myeloid cells.

a Flow cytometry analysis of the percentages of myeloid cells in peripheral blood infected with either saline (n = 4 at E8.5, n = 5 at E10.5 and n = 5 at E12.5) or H1N1 (n = 5 at E8.5, n = 5 at E10.5 and n = 5 at E12.5) at E8.5, E10.5, and E12.5. b, c Representative flow cytometry histograms (b) and corresponding quantification of the expression of IL1R2 (c) on myeloid cells in peripheral blood infected with either saline or H1N1 (n = 4 at E8.5, n = 5 at E10.5 and n = 5 at E12.5) or H1N1 (n = 5 at E8.5, n = 5 at E10.5 and n = 5 at E12.5) at E8.5, E10.5 and E12.5. d, e Representative flow cytometry histograms (d) and corresponding quantification of the expression of IL1R2 (e) on myeloid cells in lungs and deciduas infected with either saline (n = 5) or H1N1 (n = 5) at E12.5. f, g Representative images of immunofluorescence staining of CD11b and IL1R2 in lung (f) and decidua (g) sections infected with either saline or H1N1. scale bar, 20 μm. Results are representative of two or three independent experiments. All bars in the graphs represent the mean ± s.e.m. Statistical comparisons were performed using a two-tailed unpaired Student’s t test (a, c, e). Source data are provided as a Source Data file.