Table 2 Tumor response of the intention-to-treat population according to treatment arm
Arm A/A1 N = 90 | Arm A2 N = 60 | Arm B N = 60 | Arm C N = 52 | |
|---|---|---|---|---|
Complete response | 6 (7%) | 6 (10%) | 3 (5%) | 5 (10%) |
Partial response | 35 (39%) | 13 (22%) | 25 (42%) | 24 (46%) |
Stable disease | 29 (32%) | 26 (43%) | 14 (23%) | 16 (31%) |
Progressive disease | 11 (12%) | 8 (13%) | 12 (10%) | 3 (6%) |
Missing | 9 (10%) | 7 (12%) | 6 (10%) | 4 (8%) |
Objective response rate [95% CI] | 46% [35%,56%] | 32% [20%,45%] | 47% [34%,60%] | 56% [41%,70%] |
Disease control rate | 78% | 75% | 70% | 87% |
Median duration of response [95% CI] | 6.2 months [4.0;8.8] | 4.3 months [1.9;8.7] | 5.4 months [4.0;9.0] | 8.8 months [5.3; 12.6] |
Median duration of stabilization [95% CI] | 4.9 months [3.8;7.7] | 3.5 months [2.0;5.2] | 6.9 months [4.8;9.0] | 5.7 months [3.4;8.1] |
