Table 1 List of BLI-estimated steady-state binding KD values for the indicated LARP6 protein variants and RNA oligonucleotides
From: An intrinsically disordered region mediates RNA-binding selectivity and cellular activities of LARP6
RNA oligonucleotide | La-module KD (nM) | NTD KD (nM) | NTR KD (nM) |
|---|---|---|---|
U2 | 4.4 ± 0.1 | 183 ± 5.0 | |
U1 | 14.0 ± 0.8 | 587 ± 29 | |
P1 | 1.5 ± 0.4 | 61.0 ± 5.0 | 1200 ± 500 |
P2 | 0.91 ± 0.05 | 17.3 ± 1.2 | |
D1 | 2.0 ± 0.1 | 85.0 ± 4.0 | |
D2 | 6.9 ± 0.6 | 367 ± 57 | |
polyC | 63.0 ± 3.7 | >7500 |
