Fig. 10: PU-wp-LED combined with NM-NTUs alleviate IVDD in rabbits.
From: Natural photosynthetic system for restoring homeostasis of animal organelle interaction network
a Schematic diagram of the therapy. b, c Representative MRI images of rabbit IVD (b) and T2-weighted signal intensity of the NP in each group (c) (n = 4). d Macroscopic view of IVD samples. The region highlighted by the red square is shown at higher magnification. The nucleus pulposus is delineated by a red dashed circle. e The H&E, Alcian blue, and Safranin O-Fast Green staining images of IVD samples. f Histological grade evaluation according to H&E staining at 4 and 8 weeks in each group (n = 4). g Alcian blue staining quantification of rabbit IVDs at 4 and 8 weeks (n = 4). h Safranin O-Fast Green staining quantification of rabbit IVDs at 4 and 8 weeks (n = 4). i Immunofluorescence staining images of Col II and aggrecan of IVD samples. All quantitative data are the mean ± s.d. n represents the number of biologically independent samples. P values were calculated using one-way ANOVA (c, g, h) or nonparametric Kruskal–Wallis test (f). Scale bars: 400 µm (e); 200 μm (i). The regions of interest are marked by red arrows (b). Source data are provided as a Source Data file.
