Fig. 1: NAA40 and NAC co-assemble on the ribosome in vivo.
From: NAA40 and NAC cooperate in co-translational histone acetylation in humans
a SDS-PAGE gel stained with Coomassie of the elution fraction of tagged NAA40 purified under native conditions. Prominent bands were annotated based on mass spectrometry results (see Methods). b Cryo-EM density maps (top) and molecular models (bottom) of the combined hibernating ribosomes with NAA40 and NAC bound. c Cut-through view of surface representations of actively translating 80S bound with NAA40 and NAC. The translational state (top) or the nascent polypeptide chain is highlighted (bottom). d Close up view of cut throughs of the surface representations of actively translating 80S, focusing on the nascent chains (NC; left) or the distance of NAA40 to the peptide exit tunnel (right). NAC was omitted for clarity. Source data are provided as a Source data file.
