Fig. 2: Relationship between donor demographics, islet processing, islet morphology, and functional traits. | Nature Communications

Fig. 2: Relationship between donor demographics, islet processing, islet morphology, and functional traits.

From: Heterogeneous endocrine cell composition defines human islet functional phenotypes

Fig. 2: Relationship between donor demographics, islet processing, islet morphology, and functional traits.The alternative text for this image may have been generated using AI.

Heatmap of Spearman r correlation coefficients between the indicated variables in the corresponding labeled row and column. Shading represent different Spearman r values. For donor sex, the male was coded as 0 and female as 1. *p < 0.05; †p < 0.01; ‡p < 0.0001. All p-values based on the two-sided t-tests are unadjusted. The correlation coefficients and p-values are reported in Source Data Fig. 2. Abbreviations: BMI body mass index; HbA1c hemoglobin A1c; IEQ islet equivalents; INS insulin; GCG glucagon; AUC area under the curve; G glucose (mM); IBMX isobutylmethylxanthine (μM); Ad adrenaline (μM); KCl potassium chloride (mM).

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