Fig. 3: Islet secretory function is highly heterogeneous amongst donors. | Nature Communications

Fig. 3: Islet secretory function is highly heterogeneous amongst donors.

From: Heterogeneous endocrine cell composition defines human islet functional phenotypes

Fig. 3: Islet secretory function is highly heterogeneous amongst donors.The alternative text for this image may have been generated using AI.

Average (a) insulin and (b) glucagon secretion from donor islets normalized to islet equivalents (IEQs); see Source Data Fig. 3. Data are displayed as mean ± 95% confidence interval (n = 299). c Schematic and tables describing insulin and (d) glucagon secretion traits derived from individual islet secretion traces. Descriptive statistics by sex and reported race/ethnicity are provided in Supplementary Tables 1 and 2. Abbreviations: G glucose (mM); IBMX – isobutylmethylxanthine (μM); Ad – adrenaline (μM); KCl – potassium chloride (mM).

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