Fig. 6: Islet secretion traits by reported race or ethnicity. | Nature Communications

Fig. 6: Islet secretion traits by reported race or ethnicity.

From: Heterogeneous endocrine cell composition defines human islet functional phenotypes

Fig. 6: Islet secretion traits by reported race or ethnicity.The alternative text for this image may have been generated using AI.

Violin plots comparing (a) insulin and (b) glucagon secretion traits by reported race or ethnicity (n = 12 Asian (A), n = 26 Black or African American (B/A), n = 86 Hispanic or Latino/a (H/L), n = 175 White (W)). Colors represent different reported race/ethnicity. The solid line in each violin plot depicts the median, and the dotted lines represent the 1st and 3rd quartiles. Global p value is based on the one-sided F-test while controlling for the seven covariates (age, sex, BMI, HbA1c, islet isolation center, pre-shipment culture time, and islet transit time) and adjusting for multiple comparisons using the false discovery rate correction. Comparisons where the unadjusted p-value (punadj) was significant are noted in italics. P values, test statistics, and effect sizes with 95% confidence intervals are reported in Source Data Fig. 6. Abbreviations: cAMP cyclic adenosine monophosphate; KCl potassium chloride.

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