Table 1 Closed time constants obtained by single-channel kinetic analysis of wild-type rbTRPV5 channels
From: Molecular mechanism of menthol-induced TRPV5 channel inhibition
Menthol concentration, (mM) | Slow time constant ± sem, (s) | Medium time constant ± sem, (s) | Fast time constant ± sem, (s) |
|---|---|---|---|
0.0 | 64.05 ± 24.05 | 5.08 ± 2.19 | 9.0 × 10−5 ± 2.6 × 10−5 |
0.5 | 134.63 ± 9.03 | 13.36 ± 8.28 | 9.5 × 10−5 ± 4.5 × 10−6 |
1.0 | 209.93 ± 97.22 | 5.38 ± 2.58 | 8.1 × 10−5 ± 1.4 × 10−5 |
3.0 | 708.73 ± 166.89 | 8.49 ± 6.25 | 8.5 × 10−5 ± 1.5 × 10−5 |
