Extended Data Fig. 4: Structural comparison.

a, b, Density map (a) and electrostatic potential surface (b) of LciA pentamer. The intermembrane-space view (left) and cut-open view from the membrane plane (right) are shown. Each protomer is colored distinctly. The elongated lipid-like densities in the central tunnel of pentamer are colored yellow. c, Electrostatic potential surface of FNT homologs, shown in periplasmic or extracellular view. Structural models of Escherichia coli FocA (PDB: 3KCU), Salmonella typhimurium NirC (PDB: 4FC4), Clostridium difficile HSC (PDB: 3TDO) and Plasmodium falciparum PfFNT (PDB: 7E26) are shown. d, Structural comparison of a protomer between LciA and FNT homologs.