Extended Data Fig. 7: Cryo-EM image processing workflow of DCL4-DRB4CTD-dsRNA complex.

a, A representative cryo-EM image of DCL4-DRB4CTD-dsRNA complex. b, Flowchart of cryo-EM data processing. c, 2D class averages. d, Gold-standard Fourier shell correlation (GSFSC) of the final map. e, Angular distribution heat map calculated in cryoSPARC for particle projections contributing to the local resolution. f, Cryo-EM maps showing the fitting of the representative protein and RNA regions.