Fig. 5: VB12 extends a healthy lifespan and enhances cognitive function through the regulation of ptp-3.
From: PTP-3 regulated by VB12 is important for ageing health in C. elegans
A VB12 supplementation slows neuronal degeneration in PVD dependent on the ptp-3 gene. B VB12 supplementation to prolong nematode life depends on ptp-3 gene. C The supplementation of VB12 and the overexpression of the ptp-3 gene both prolong the lifespan of the nematodes, but they do not act synergistically. D–F Learning is dependent on ptp-3 gene supplementation of VB12 to PA14, chemical reagents and temperature.
