Fig. 1: Alterations in Peripheral B Cell Subsets in POI Patients. | npj Aging

Fig. 1: Alterations in Peripheral B Cell Subsets in POI Patients.

From: Peripheral B cell alteration in patients with premature ovarian insufficiency

Fig. 1

A Representative flow cytometry plots depicting total B cells in peripheral blood of POI patients, with corresponding statistical analysis illustrating changes in B cell number and proportion. B Flow cytometry-based analysis showing distribution of B cell subsets in POI patients, with a statistical chart demonstrating relative proportions of these subsets. Total B cells: control (n = 63), POI (n = 51); other subsets: control (n = 35), POI (n = 23). Total B cells, transitional B cells, and plasmablasts were compared by two-tailed Mann–Whitney U test; naïve B cells, class-switched and non-class-switched MBCs by Dirichlet regression. * p < 0.05, **** p < 0.0001.

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