Fig. 2: L. plantarum OL3246 administration improved markers of protein oxidation, stabilized SOD levels, and lowered production of ∝-synuclein. | npj Aging

Fig. 2: L. plantarum OL3246 administration improved markers of protein oxidation, stabilized SOD levels, and lowered production of ∝-synuclein.

From: Probiotic Lactiplantibacillus plantarum OL3246 supports healthy aging by enhancing quality of life, reducing inflammation, and modulating gut microbiota: a pilot study

Fig. 2: L. plantarum OL3246 administration improved markers of protein oxidation, stabilized SOD levels, and lowered production of ∝-synuclein.

Pre/Post comparisons of AOPP (a; orange-pre, blue-post) and SOD (b; orange-pre, purple-post) between the Placebo and Intervention group have been made using REML ANOVA with Tukey post-hoc comparison; outliers have been filtered using the IQR method. Delta—change of ∝-synuclein (c) has been compared using the Welch t-test. Delta’s of SOD and ∝-syn have been correlated (d; grey—placebo; green—L. plantarum OL3246) by the Pearson method—R and p values are presented in the plot. Significance code: ns—non-significant, *p < 0.05, **p < 0.01, *** p < 0.001, ****p < 0.0001.

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