Fig. 3: Differential host transcriptome in LRTIs patients versus non-LRTIs patients.

A Heatmap of host differential expressed genes, these genes were grouped into three sub-sets, each set presenting different KEGG pathway enrichment indicated by the pie chart. B Network of lineages of genes and KEGG pathways, big nodes present pathways, and small nodes present genes colored by log2 fold change. C Dot plot of DOSE enrichment of host differential expressed genes, each dot presents a significantly enriched disease, and the size of the dot indicates enriched gene number. FDR was applied to the color dot.