Table 2 MIC of first-line antibiotic resistant strains

From: Adaptation mechanisms of Clostridioides difficile to auranofin and its impact on human gut microbiota

Strain

Drug

Epidemiological cut-off (µg mL−1)

MIC 1st ATB (µg mL−1)

MIC auranofin (µg mL−1)

630∆erm

/

/

/

0.750

CD19-071

Fdx

0.5

16

0.375

CD18-314

Van

2

1.5

1.500

CD19-017

1.5

0.750

CD19-230

1.5

1.500

CD20-059

2

0.750

104-1

Mtz

2

16

1.500

804

4

1.500

861

8

0.750

91861-2

16

0.750

985 642

8

0.750

985 827

8

0.750

  1. The epidemiological cut-off100 and the MIC for the first-line treatment are indicated. The MIC for AF was determined using the liquid two-fold serial dilution method. The experiment was performed in four biological replicates.
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