Fig. 2: Baseline gut microbiome.

A Effect sizes of moisture covariate on microbiome community variation (stepwise dbRDA on Bray-Curtis dissimilarity for the mOTU and Canberra distance for the GMM) B Principal Coordinate analysis of gut microbiome composition (mOTU level) and (C) function (GMM) D Significant association between richness and some microbial and host markers (Spearman’s ρ, FDR < 0.1) E Enterotyping of the gut microbiome in our baseline study cohort (N = 79), FGFP young adults (N = 199) and FGFP older adults (N = 2799).