Fig. 1: In silico screening, targeting the L-lectin module of a major virulence factor, SraP, against a database consisting of ~14,000 natural products, identified 10 natural products with a high-affinity binding. | npj Biofilms and Microbiomes

Fig. 1: In silico screening, targeting the L-lectin module of a major virulence factor, SraP, against a database consisting of ~14,000 natural products, identified 10 natural products with a high-affinity binding.

From: Exploiting strong synergies between punicalagin and cefoperazone to combat methicillin-resistant Staphylococcus aureus infections

Fig. 1

A The putative binding sites of the 10 compounds to SraP predicted by Autodock Vina. B Binding free energy and putative binding sites. C The minimum inhibitory concentration (MIC) of the 10 natural compounds, defined as the lowest concentration that completely (100%) prevents visible growth of methicillin-resistant Staphylococcus aureus (MRSA) test strain MW2 under in vitro conditions (MIC100).

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