Fig. 3: Inhibition of biofilm formation by JT71. | npj Biofilms and Microbiomes

Fig. 3: Inhibition of biofilm formation by JT71.

From: Chemical inhibition of MrkH-dependent activation of type 3 fimbriae synthesis and biofilm formation by Klebsiella pneumoniae

Fig. 3

Biofilm formation of K. pneumoniae AJ218 on uncoated polystyrene (a) and type IV collagen-coated polystyrene (b) grown in the presence of varying concentrations of JT71 or equivalent concentrations of DMSO solvent used. Biological replicates (n = 25–30) are pooled from three independent assays, and the mean ± 95% CI for each group is shown. c Biofilm formation of K. pneumoniae (Kp), C. koseri (Ck), and P. aeruginosa (Pa) strains grown with or without 50 µM JT71. Data are the mean ± 95% CI of biological replicates pooled from three independent assays. Each JT71-treated group was compared to controls that were treated with equivalent amounts of DMSO solvent using two-way ANOVA with the Bonferroni post-test, *P < 0.05; ***P < 0.001; ****P < 0.0001.

Back to article page