Table 1 Concentration of chitosan hyrdogel (CH), fosfomycin (FOS), and polylactic acid-fosfomycin (PLA-FOS) in each biomaterial delivery vehicle for in vitro and in vivo experiments
Concentration of components [mg/mL] | ||||||
|---|---|---|---|---|---|---|
Biomaterial groups | CH | FOS | PLA-FOS | |||
Experiments | In vitro | In vivo | In vitro | In vivo | In vitro | In vivo |
CH | 40 | 40 | – | – | – | – |
CH-FOS | 40 | 40 | 5 | 333 | – | – |
CH + PLA-FOS | 40 | 40 | – | – | 10 | 667 |
CH-FOS + PLA-FOS | 40 | 40 | 2.5 | 167 | 5 | 333 |
PBS-FOS | – | n/a | 5 | n/a | – | n/a |
