Fig. 10: FMT on intestinal inflammation and mucosal integrity. | npj Biofilms and Microbiomes

Fig. 10: FMT on intestinal inflammation and mucosal integrity.

From: Alternate-day fasting ameliorates α-synuclein pathology and suppresses inflammation via the gut-brain axis in an MPTP-induced subacute mouse model of Parkinson’s disease

Fig. 10

a Representative IF staining of ZO-1 (green) and Occludin (green), IHC staining of IL-1β and HE staining of gut. Scale bars = 100 μm (IF staining) and 200 μm (IHC and HE staining). b Representative western blot of Occludin. c The statistical graph of Occludin in the gut. NS+PBS versus MPTP + PBS: p < 0.001; MPTP + PBS versus MPTP + MPTP-ADF: p = 0.180. Relative optical density was normalized to GAPDH (n = 6). d The statistical graph of mean fluorescence intensity of ZO-1(n = 6). NS + PBS versus MPTP + PBS: p < 0.001; MPTP+PBS versus MPTP + MPTP-ADF: p = 0.006. e The statistical graph of mean fluorescence intensity of Occludin (n = 6). NS+PBS versus MPTP + PBS: p = 0.003; MPTP + PBS versus MPTP + MPTP-ADF: p = 0.560.

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