Fig. 7: Venn diagram representation of functions and function-level similarities and differences among the paired vaginal, endocervical and rectal microbiomes for the three cohort datasets at baseline and follow-up timepoints.

The size of the circle represents the number of function-level pathways comprising that circle. Supplementary Tables S7–S12 show the pathways associated with each function for each anatomic site and whether pathways are shared among two or three sites. Vaginal, endocervical and rectal sites are represented as blue, red and yellow, respectively; overlap between two or all three sites are represented in the color key. Red font denotes functions and pathways unique to a particular anatomic site or shared anatomic site.