Fig. 7: C. spp. and wogonin promote conjugated bile acid metabolism. | npj Biofilms and Microbiomes

Fig. 7: C. spp. and wogonin promote conjugated bile acid metabolism.

From: Synergistic effects of ferulic acid and wogonin on cholestatic liver injury via gut microbiota modulation

Fig. 7

A Liver total bile acid concentrations in indicated groups. B Serum bile acid concentrations in the ANIT and C. spp. groups. C Fecal total bile acid concentrations were determined in indicated groups. D BSH enzyme activity in feces. E Bile acid concentrations in the serum between ANIT and Wog treatment group. F Liver total bile acid concentrations were determined in indicated groups. G Fecal total bile acid concentrations were determined in indicated groups. Data are represented as mean ± SEM (n = 5). *p < 0.05, **p < 0.01. ANIT alpha-naphthyl isothiocyanate, Wog wogonin, C. spp. Clostridium spp., BAs bile acids, BSH bile salt hydrolase, TDCA taurodeoxycholic acid, TLCA taurolithocholic acid, GLCA glycolithocholic acid, GCA glycocholic acid, TCA taurocholic acid, TUDCA tauroursodeoxycholic acid, T-α-MCA tauro α-Muricholic acid, T-β-MCA tauro β-Muricholic acid, THDCA taurohyodeoxycholic acid, TCDCA taurochenodeoxycholic acid, DCA deoxycholic acid, LCA lithocholic acid, CA cholic acid, UDCA ursodeoxycholic acid, α-MCA α-Muricholic acid, β-MCA β-Muricholic acid, HDCA hyodeoxycholic acid, CDCA chenodeoxycholic acid.

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